Pentobarbital (Nembutal) Powder

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When we talk about sedatives and euthanasia, Nembutal powder is one of the products that come up in mind. Nembutal powder history goes back to many decades ago. In the past, Nembutal was very popular for its effective use in treating anxiety and sleeping disorders. However, this is not the case anymore since most pharmaceuticals no longer produce Nembutal and other barbiturates. The drug is severely lethal in high dosages, which makes it a go to drug for those who want to commit suicide or conduct euthanasia.

Because it is easy to overdose when under Nembutal powder treatment, the drug is hard to find nowadays since most pharmaceuticals have replaced the drug with much safer drugs. Nembutal powder is however still popular among veterinaries for its use in euthanizing large animals.    

What is Nembutal Powder?

Nembutal is a name that John S Lundy coined in the 1930s. The drug belongs to a group of drugs called barbiturates and works by reducing the activities of the central nervous system and the brain. The drug was most popular in the 50s and 60s for treating sleep disorders. Medical practitioners also used it to treat seizures and for other purposes not listed here.

Some crucial information about Nembutal powder

It is not advisable for people who are allergic to Nembutal or any other barbiturates to use this dug. People with porphyria should also avoid using Nembutal powder. This genetic enzyme condition affects the skin and the central nervous system.

Nembutal can be addictive and habit forming and people without a prescription should not take it. For this reason, you should never share this drug with other people especially those with a history of substance abuse.

Nembutal powder can have severe side effects that can impair your judgement or your reasoning so you should avoid engaging in tasks that require you to be awake.

Avoid taking alcoholic drinks if you are taking Nembutal powder unless you want to end your life. Alcohol helps speed up the effects of Nembutal.

Nembutal affects the effectiveness of birth control pills. If you are under Nembutal treatment, use non-hormonal birth control ways such as condoms to make sure you do not get pregnant.

Nembutal pentobarbital sodium powder

The uses of Nembutal powder

As said earlier, people mostly used Nembutal powder for treatment of sleeping disorders. However, after most nations banned it, other safer drugs and sleeping pills replaced it. The drug is however still available in most nations especially for euthanizing animals. In laboratories, the drug is strictly for medical reasons such as sedation and anesthesia.


  • Pre anesthetics
  • Sedative
  • Anticonvulsant
  • Hypnotics for short-term insomnia treatment

What will happen if you overdose on Nembutal powder?

Overdosing on any barbiturate leave alone Nembutal can be very fatal. Since they are central nervous system suppressants, you are likely to suffer fatal effects in case of an overdose. You should get medical help immediately if you suspect you have taken too much of this drug. The effects of a Nembutal overdose can be severe. Signs of an overdose include dilated pupils, weak feeling, lack, or less urinating, fast, or slow heart rate, weak pulse, fainting or slow breathing.

In worst cases, a Nembutal overdose can cause a physical damage to the brain and other vital organs such as the kidney and even death.

What happens in case of a missed Nembutal Dose?

Most patients take Nembutal when there is need to so there is less chance of a missed dose. However, if you take the drug regularly and you miss your dose, then you should take the missed dose immediately. You should skip the dose if it is almost time for the next dose. You should not take an extra dose to make up for the missed dose. You risk overdosing if you do this.

Some of the Nembutal side effects

Almost all barbiturates have side effects. Some of them can be mild while others are severe. One of the most common side effect is habit forming and addiction. People who take Nembutal for long mostly develop withdrawal symptoms when they stop taking the drug. Nembutal also has the possibility of causing several allergic reactions such as hives, difficulty breathing, and swelling of face, lips, tongue, or throat. Other effects can be confusion, hallucination; weak or shallow breathing, slow heart rate, weak pulse, and a feeling like you want to pass out.

Some of the less severe side effects include:

  • Poor concentration or memory loss
  • Excitement, irritability, or aggression
  • Loss of balance or poor coordination
  • Nightmares
  • Nausea, vomiting, and constipation
  • Hangovers or a headache

It is worth noting that other side effects might occur. Contact your doctor if you notice anything out of the ordinary.

Nembutal powder dosage

The dosage of Nembutal depends on the purpose and it varies from one person to another.

The Lethal overdose experimented after consumption is as follow:

20 grams lethal dose for a person 1kg – 50kg
35 grams lethal dose for a person 51kg – 75kg
50 grams lethal dose for a person 76kg – 90kg
75 grams lethal dose for a person 91kg – 100kg
100 grams lethal dose a person 100kg – Above

If you are taking Nembutal for treatment purposes, ask your doctor on the correct doses that you should take. Your doctor will conduct tests that will ensure you are taking the correct dosage.

What is the legal status of Nembutal powder?

Nembutal powder has the classification of a schedule 2 drug meaning you risk a long jail term or a hefty fine if you are caught selling or buying Nembutal. Since it is a controlled drug, you need a prescription from a qualified doctor to purchase.


Although this is not everything about Nembutal powder, the information provided is crucial to anyone who wants to learn about Nembutal powder.