Pentobarbital (Nembutal) Injection Solution

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Pentobarbital is not a new word for those who are familiar with chemicals. It is a short acting barbiturate that is very effective as a hypnotic and sedative agent and you normally take it orally. Doctors prescribe it more frequently to induce sleep than for sedation but like similar drugs, pentobarbital intravenous solution might lose its effectiveness by the second week of continued administration.  The half-life of the drug is 5-50 hours depending on the dose.

Pentobarbital was very common in the past but now it has become very expensive and is no longer accessible as an anesthetic in most parts of the world.

What is pentobarbital?

Pentobarbital Sodium Injection 20ml

It is a barbiturate that acts by slowing down the activities of the CNS and the brain. In a medical setup, physicians use this medication as a sedative, an anesthetic or as a short-term treatment for insomnia. It can also be used for emergency treatment for epilepsy, insomnia and other related conditions. Doctors also use the drug in vascular neurosurgery.

Is it possible to obtain pentobarbital legally?

Pentobarbital is one of the few drugs you can buy legally. However, the number of pharmaceuticals that manufacture pentobarbital has drastically reduced which makes it hard to obtain it. A doctor needs to recommend the drug and give you a prescription for you to get the drug.

Psychologic effects of Pentobarbital intravenous solution

Pentobarbital can have several physiologic effects such as arrest or depression, reduced arterial blood pressure, reduced cardiac output, peripheral vasodilation, vasopressor response depression to hemorrhage and increase or preservation in heart rate. Pentobarbital can influence research variables. For instance, it reduces myocardial damage after coronary artery ligation.

Pentobarbital produces the desired sedation depth associated with the Jorgensen technique. It is also the drug that provides the 2-4 hour period of action associated with the Jorgensen method. As a central nervous depressant, pentobarbital has a disquieting effect of causing patients more likely to overact to stimulation.

For many years, Pentobarbital has been the most common laboratory animal anesthetic. Surgical anesthesia is achieved in most small lab animals only when dosage close to those that cause respiratory failure are administered. Slow intravenous administration of a dose enough to produce basal narcosis followed by further incremental doses mostly achieves surgical anesthesia levels reasonably safely.

Note that pentobarbital is no longer commercially available as an anesthetic in most nations. However, you can purchase the drug from specialist suppliers if you need it for specific research projects.

Is Pentobarbital intravenous solution addictive?

Pentobarbital Sodium Injection 50ml

Yes, just like other barbiturates, pentobarbital is very addictive. Never take more than the required amount or less than recommended amount. It should not be administered for longer periods than recommend. You should also consult a doctor before you withdrawal from the drug. Failure to do that can result to withdrawal symptoms such as insomnia, dizziness, fainting and much more. The doctor knows how to reduce your dosage gradually to avoid severe withdrawal symptoms.

Signs of a Pentobarbital intravenous solution overdose

Overdosing on barbiturates is easy and the effects are fatal if you don’t get medical help immediately. Below are some of the common overdose signs.

  • Rapid or weak pulse
  • Nausea and vomiting
  • Drowsiness
  • Confusion or irritability
  • Constricted pupils
  • Low blood pressure and temperatures
  • Dizziness and headaches
  • Anxiety and nervousness
  • Nightmares and hallucinations
  • Shallow and weak respiration
  • Loss of coordination and balance
  • Flat EEG results
  • Reduced mental alertness

The above symptoms should be a caution you are experiencing an overdose on pentobarbital. A severe overdose can result in a coma, respiratory depression that can cause death. Seek medical attention immediately if you notice these signs.

Are there treatment options if you overdose on pentobarbital?

As we have said above a pentobarbital overdose can be fatal. Always tell your doctor if you are sensitive to barbiturates or you have a history of drug abuse. Additionally, tell you doctor if you have porphyria, renal or liver disease, uncontrolled asthma, chronic obstructive pulmonary condition, and a history of chronic pain or mental illness. If you suspect someone has overdosed, don’t try to make him or her vomit but seek immediate medical help. Mostly, treating pentobarbital overdose is supportive. Below are some common treatment procedures:

  • Monitoring the vital signs of an overdose
  • Monitoring the intake and output of fluid
  • Maintaining the safety of the victim at all times
  • Ensuring there is sufficient oxygen
  • Monitoring the shock symptoms
  • Increasing fluid intake
  • Promoting renal excretion of pentobarbital
  • Monitoring consciousness levels
  • Maintaining aspiration precautions
  • In cases of abnormal renal function, hemodialysis might be required to get the drug from the system
  • Antibiotic therapy if the complication is pneumonia
  • Providing care that can solve the signs of altered thinking and mental alertness
  • Monitoring possible complications like pulmonary edema, renal failure, congestive heart problems and arrhythmias.     

What are pentobarbital side effects?

It’s possible to experience some side effects after taking pentobarbital both mild and severe. The list below includes some of the most common effects. They are: agitation, confusion, hallucinations, nightmares, nervousness, anxiety, insomnia, abnormal thinking, dizziness, nausea, vomiting, constipation, headaches, and fever among others.

Remember that this is not a complete list of the side effects. Others might occur.

Can you purchase pentobarbital online?

If you search on Google, you will find many online shops promising to sell you legitimate pentobarbital. However, it is worth noting pentobarbital and other barbiturates are restricted drugs in most nations so there is no way they are easily available. If you decide to buy pentobarbital online, it is wise to consider your safety. Do proper research to ensure that the vendor selling the drug to you is legitimate.